If there’s one thing my family knows, it’s that game day isn’t complete without something warm, cheesy, and completely irresistible on the menu. These Slow Cooker Mississippi Pot Roast Sliders have quickly become a staple in our house for big gatherings, Sunday football, and even easy weeknight dinners. The beef cooks low and slow all day in that famous Mississippi Pot Roast mix—ranch, au jus, butter, and pepperoncinis—until it’s so tender you can shred it with a fork.

Slow Cooker Mississippi Pot Roast Sliders stacked on a plate sitting on a table

When the beef is piled onto soft slider rolls, topped with melty provolone cheese, and brushed with a garlicky butter glaze before baking, the result is an over-the-top, flavor-packed little sandwich that disappears almost as fast as you can make them. My husband loves loading his up with extra pepperoncinis for more tang, while the kids go for the gooey, cheesy middle. Either way, these sliders never last long!

Slow Cooker Mississippi Pot Roast Sliders stacked on plate with a red checkered towel under the plate

What Are Slow Cooker Mississippi Pot Roast Sliders?

At their core, these sliders are a fun twist on the classic Mississippi Pot Roast—one of the most popular slow cooker recipes on the internet. Instead of serving the shredded beef over mashed potatoes or rice, we’re turning it into the ultimate party food: cheesy, handheld sliders. The flavor profile stays true to the original—savory, rich, tangy, and buttery—while the presentation makes them perfect for feeding a crowd.

Slow Cooker Mississippi Pot Roast Sliders on a plate with drinks behind it and a jar full of wooden kitchen utensils

When to Serve

These sliders are incredibly versatile and fit into just about any occasion:

Game Day Parties – The ultimate crowd-pleaser while everyone’s glued to the TV.
Holiday Gatherings – Works as an appetizer or as part of a casual buffet.
Potlucks – Travels well in a covered baking dish.
Family Dinners – Serve with a big salad or roasted veggies for an easy meal.
Meal Prep Lunches – Pack in lunchboxes for a hearty option that reheats well.

overhead look of Slow Cooker Mississippi Pot Roast in the pan

Why You’ll Love These

Hands-Off Cooking – The slow cooker does all the heavy lifting.
Incredible Flavor – Tangy pepperoncinis, savory ranch, and au jus work magic on the beef.
Perfect for a Crowd – Makes a dozen sliders without doubling the recipe.
Customizable – Change up the cheese, add toppings, or spice it up.
Kid-Friendly – The tangy flavor is balanced by the buttery, cheesy finish.

Slow Cooker Mississippi Pot Roast Sliders ingredients all on single serve containers sitting on table

Ingredient Breakdown

Chuck Roast (3 pounds) – The go-to cut for pot roast thanks to its marbling. It becomes incredibly tender after slow cooking.
Ranch Dressing Mix (1 ounce) – Adds herby, savory seasoning.
Au Jus Gravy Mix (1 ounce) – Brings depth and beefy richness.
Butter (¼ cup) – The secret to that silky, rich sauce.
Pepperoncini Peppers (½ cup sliced + juice) – Gives the signature tangy kick.
Hawaiian Rolls (12 count) – Soft and slightly sweet, the perfect contrast to savory beef.
Provolone Cheese (12 slices) – Melts beautifully and pairs well with the beef’s flavors.
Extra Pepperoncinis for Topping (¼ cup) – Adds brightness and heat.
Butter, Garlic Salt, Parsley (for brushing) – The finishing touch that makes the tops golden, flavorful, and bakery-worthy.

raw pot roast with sauce, butter and peppers

Slow Cooker Mississippi Pot Roast in a slow cooker with more peppers on top

Variations

Spicy Upgrade – Use hot pepperoncinis or add sliced jalapeños.
Garlic Bread Style – Brush rolls with garlic butter and sprinkle with Parmesan before baking.
Pork Version – Use a pork shoulder instead of beef.
Open-Faced Option – Serve on toasted garlic bread instead of closed sliders.

Mississippi Pot Roast Sliders stacked on a plate with glasses behind the plate

Best Cheese for Mississippi Pot Roast Sliders

While provolone is a classic choice for its smooth melt and mild flavor, you can easily tailor these sliders to your taste or the crowd you’re serving. Mozzarella offers a milder profile with a stretchy pull, Swiss brings a nutty note that complements the tangy pepperoncinis, and pepper jack adds just the right amount of heat for spice lovers. For maximum richness, try combining two cheeses—like provolone and mozzarella—for a gooey, bakery-style melt that covers every bite.

Slow Cooker Mississippi Pot Roast Sliders stacked on a plate with a close up of sliders on table

Troubleshooting

Cheese Didn’t Melt – Cover the baking dish with foil for the first half of baking, then uncover to brown.
Too Salty – Use unsalted butter and low-sodium gravy mix.
Not Enough Flavor – Add extra pepperoncini juice or a sprinkle of garlic powder before baking.

How to Keep Slider Rolls from Getting Soggy

One of the most common concerns with slow cooker Mississippi pot roast sliders is soggy bread, but there are a few easy tricks to avoid it. Always drain excess cooking liquid from the shredded beef before layering it onto the rolls. Toasting the bottom half of the rolls for 3–4 minutes in the oven before assembly can create a barrier that helps them hold up longer. You can also place a slice of cheese directly on the bottom roll before adding the meat—this creates a buffer and helps keep your Hawaiian rolls for sliders light and fluffy even after baking.

Storage and Serving Tips

Refrigeration – Store leftover sliders in an airtight container in the fridge for up to 3 days.
Reheating – Wrap in foil and warm in a 325°F oven for 10–15 minutes.
Serving Crowd-Sized Batches – Keep them warm in a low-heat oven until ready to serve.
Pairing Ideas – Serve with chips, a green salad, coleslaw, or roasted veggies.

Make-Ahead and Freezing Tips

Make-Ahead – Cook the beef up to 2 days in advance, then assemble and bake sliders just before serving.
Freezing the Beef – Shredded beef freezes beautifully for up to 3 months. Thaw overnight in the fridge before reheating.
Do Not Freeze Assembled Sliders – The bread will lose texture when thawed.

Slow Cooker Mississippi Pot Roast Sliders stacked on a plate with a towel under it with some glasses behind it on table

Lightened-Up Version

Use a leaner chuck roast and trim visible fat.
Swap regular cheese for reduced-fat slices.
Use a light butter substitute for the brushing glaze.
Serve open-faced to cut down on bread.

Protein Swaps & Dietary Adjustments

Protein Options – Swap the chuck roast for pork shoulder, boneless skinless chicken thighs, or turkey breast for a lighter twist.
Low-Sodium Adjustments – Use unsalted butter and low-sodium ranch/au jus packets to reduce salt content.
Dairy-Free – Skip the cheese or use a plant-based alternative.
Keto-Friendly – Serve the beef in lettuce wraps or on low-carb slider buns.

Slow Cooker Mississippi Pot Roast Sliders on a plate with some dishes behind the plate full of burgers

Budget Breakdown (approximate, based on average U.S. grocery prices)

Chuck roast (3 lb) – $15.00
Ranch mix – $1.00
Au jus mix – $1.00
Butter – $0.75
Pepperoncinis – $2.50
Hawaiian rolls – $4.50
Provolone – $3.50
Garlic salt, parsley – $0.50

Total: ~~$28.75 for 12 sliders (~~$2.40 per slider)

close up of Slow Cooker with Mississippi Pot Roast inside

Beginner Mistakes to Avoid

Skipping the Juice – The pepperoncini juice is key for authentic flavor.
Overcooking in the Oven – Just bake until cheese melts and tops are golden.
Not Slicing Rolls Evenly – Uneven cuts can cause toppers to slide off during baking.
Adding Meat Too Wet – Drain well to keep rolls intact.

Slow Cooker Mississippi Pot Roast Sliders on a table setting with glasses, cutting board and drink glasses behind it on table

FAQ (Detailed for SEO)

Q: Can I make these in an Instant Pot?
A: Yes, but you’ll need to adjust the liquid slightly and cook on high pressure for about 60 minutes with natural release.

Q: Do I have to use Hawaiian rolls?
A: No, you can use dinner rolls, mini brioche buns, or any small soft roll.

Q: What if I can’t find pepperoncinis?
A: Banana peppers are a good substitute, though they’re slightly sweeter.

Q: Can I make these spicier?
A: Use hot pepperoncinis, add red pepper flakes, or top with jalapeños.

Q: Can I use pre-sliced deli roast beef?
A: You can, but the texture and flavor won’t be the same as slow-cooked chuck roast.

Q: How do I keep sliders warm for a party?
A: Place them in a covered baking dish in a 200°F oven until ready to serve.

Q: Is there a gluten-free option?
A: Yes, use gluten-free rolls and ensure your gravy and ranch packets are GF-certified.

close up of Slow Cooker Mississippi Pot Roast Sliders on a plate with a red checkered towel under it

Hosting Tip: DIY Slider Bar

For parties, keep the shredded beef warm in the slow cooker and set out trays of slider rolls, cheeses, and toppings like sliced jalapeños, extra pepperoncinis, sautéed mushrooms, and caramelized onions. Guests can build their own sliders exactly how they like them—perfect for accommodating different spice levels and preferences.

Personal Kitchen Notes

I’ve made these sliders for both big family gatherings and quiet Sunday dinners, and they’re always a hit. The key for me is to drain the beef well before layering it on the rolls—otherwise the bread can get too soft. I also like to assemble them in the morning and keep them covered in the fridge until just before baking so the prep feels effortless when guests arrive. If I’m making them for game day, I’ll keep a second batch of the shredded beef warm in the slow cooker so I can quickly assemble more sliders if the first tray vanishes (which it usually does).

Slow Cooker Mississippi Pot Roast Sliders stacked on a plate with some glasses and ceramic containers behind it on table

Final Thoughts

If you’re looking for a recipe that’s guaranteed to disappear before halftime, Slow Cooker Mississippi Pot Roast Sliders are it. They’re everything you want in a party food—easy to make, ridiculously flavorful, and loved by kids and adults alike. Whether you’re hosting a football party, a holiday get-together, or just want an effortless family dinner, this is one recipe you’ll come back to again and again.

Slow Cooker Mississippi Pot Roast Sliders (Easy & Flavorful)